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Center of Biomedical Research Excellence

 

 

 

Center of Biomedical Research Excellence (COBRE)

Immune-Based Interventions Against Infectious Diseases

Infectious diseases continue to represent major causes of death and disease worldwide. Our Center of Biomedical Research Excellence (COBRE) seeks to address the challenge of new and emerging infectious diseases by advancing the development of a multidisciplinary and trans-institutional research program in infectious diseases immunology. The unifying scientific theme of our COBRE is translational research at the interface of the pathogen and host. Our COBRE is a partnership between the Institute for Immunology and Informatics (iCubed) at the University of Rhode Island’s Providence campus and the Center for International Health Research (CIHR) at Rhode Island Hospital.

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Specific COBRE AIMS

Fostering an interactive research community in translational infectious diseases immunology research in the Providence, RI, area through:

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  • Seminars and Journal Club

Enhancing the infrastructure for immunology research through Research Cores:

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    • Statistics and Data Management (Core Leader- Jennifer Friedman, M.D., Ph.D, M.P.H.)
    • Cell Analysis and Sorting (Core Leader- Loren Fast, Ph.D.)
    • High-Throughput Multiplexed Immunoassays (Core Leader- Jonathan Kurtis, M.D., Ph.D.)

Expanding infectious diseases immunology research by junior investigators through recruitment, research support, and mentoring by senior investigators:

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  • COBRE Research Projects
    • Autophagy Regulation of Innate and Adaptive Immunity in Dengue (Project Leader- Carey Medin, iCubed)
    • HIV Exposed-Uninfected Infant Immunity (Project Leader- Barbara Payne, iCubed)
    • Novel Vaccine Candidate for Pediatric Falciparum Malaria (Project Leader- Ian Michelow, CIHR)
    • Cellular Effector Mechanisms Elicited by Novel Malaria Vaccine Candidate PfSEA-1 (Project Leader- Christian Nixon, CIHR)
  • COBRE Pilot Projects Program

Center of Biomedical Research Excellence

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Centers of Biomedical Research Excellence Participataing Institutions in Rhode Island

COBRE Center for Cancer Signaling Networks Brown University
COBRE Center for Cancer Research Development Rhode Island Hospital
COBRE Center for Central Nervous System Function Brown University
COBRE for Perinatal Biology Women and Infants Hospital of Rhode Island
COBRE for Skeletal Health and Repair Rhode Island Hospital
Vascular Biology COBREOcean State Research Institute
Immune-Based Interventions Against Infectious Diseases University of Rhode Island
Stem Cell Biology: New Directions in Clinical and Basic ResearchLifespan

COBRE Partners

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