Brown professor decoding liver disease and Hepatitis C

Gregory_pic-150x150iCubed’s “Featured Researcher of the Month” for June 2013 is Dr. Stephen Gregory. Dr. Gregory is an associate professor of medicine at Brown University’s Alpert Medical School as well as a principal investigator on iCubed’s $13 million TRIAD U19 grant from the National Institutes of Health.

Dr. Gregory’s current projects include studying the factors affecting cholestatic liver disease (mouse model) and Hepatitis C (HCV), specifically, vaccine production and the factors that influence spontaneous viral clearance versus the development of chronic disease. Previous projects for Dr. Gregory include the study of endotoxin/polyclonal B cell activation, osteoclasts/bone resorption/periodontal disease, and the role of the liver in host defenses to systemic infections (Listeria model).

In the future, Dr. Gregory plans to research the effect of HIV/HCV co-infection on the response to virus-specific epitopes as well as research a Hepatocellular Carcinoma (HCC) vaccine with Brown University colleagues Dr. Ramratnam and Dr. Wands respectively.

Dr. Gregory earned his Ph.D. from St. Louis University.